In recent, biotech companies in the US have been receiving increased investments, after a few years of challenges that saw many companies suffer financial crisis, leading to job cuts, and even closure.
The US has always been a leader in the biotech industry. Vision Research Reports estimated that the US biotech market was valued at 552.43 billion in 2023, and is expected to grow to USD 1,785.96 billion by 2033, at an annual CAGR of 12.45%.
As a global biotech leader, US is home to major biotech clusters. Prominent among them are Boston/Cambridge, Massachusetts, San Francisco Bay Area, and San Diego in California, Raleigh-Durham, North Carolina (known as the Research Triangle), BioHealth Capital Region (Maryland, Virginia, and Washington, D.C.), Chicago, Illinois, Philadelphia, New York, New Jersey, and Seattle.
The biotech sector in the US is highly diverse, and encompass areas such as human health (which accounts for a large share of the market), agriculture, environmental, and industrial biotechnology.
In the area of human health, top segments include CRISPR and other gene-editing, immunotherapy, synthetic biology, biopharmaceuticals (monoclonal antibodies and recombinant proteins), AI-guided therapies, precision medicine, next generation sequencing and bioinformatics
Top Biotech Companies in the US
United Therapuetics Corporation, co-headquartered in Silver Spring, Maryland and Research Triangle Park, North Carolina
Amyris, Inc., headquartered in Emeryville, California
Twist Bioscience, based in South San Francisco
Novo NordiskUSA, headquartered in Plainsboro Township, New Jersey
Eli Lilly and Company, headquartered in Indianapolis, Indiana
Amicus Therapeutics, based in based in Philadelphia, Pennsylvania.
Pfizer Inc, based at The Spiral in Manhattan, New York City.
Novartis AG, a Swiss multinational pharmaceutical, with its US headquarters at East Hanover, New Jersey. The global research operations, called “Novartis Institutes for BioMedical Research (NIBR)” global headquarters is in Cambridge, Massachusetts.
Amgen, headquartered in Thousand Oaks, California
Gilead Sciences, based in Foster City, California.
Johnson & Johnson, headquartered in New Brunswick, New Jersey
Vertex Pharmaceuticals, based in Boston, Massachusetts
Sanofi, with its North American headquarters at Bridgewater, New Jersey
Regeneron Pharmaceuticals, based in Westchester County, New York
Novo Nordisk, based in Plainsboro, New Jersey.
BioMarin Pharmaceutical, headquartered in San Rafael, California.
Takeda Pharmaceutical, a Japanese company based in Cambridge, Massachusetts.
AstraZeneca, a British company, with its US base in Wilmington, Delaware.
Merck & Co., Inc, based in Rahway, New Jersey.
Bristol-Myers Squibb, based in Princeton, New Jersey
Biogen, based in Cambridge, Massachusetts
GSK, a British biopharma, with locations in Durham, North Carolina, and Philadelphia, Pennsylvania.
Thermo Fisher Scientific, with its base in Waltham, Massachusetts,
List of Biotech Companies in the US (Individual States)
